How does a cell move materials across its membrane to maintain homeostasis?
Determine the role of cellular transport (diffusion, osmosis, facilitated diffusion, and active transport) across the selectively permeable membrane in maintaining homeostasis (GSE SB1.d).
A Georgia Milestones Biology EOC answer on cellular transport: the selectively permeable membrane, passive transport (diffusion, osmosis, facilitated diffusion) versus active transport, predicting water movement in hypotonic, hypertonic, and isotonic solutions, and how transport maintains homeostasis.
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What this topic is asking
Standard SB1.d asks you to determine the role of cellular transport in maintaining homeostasis. For the Georgia Milestones Biology EOC you must distinguish passive transport (no energy) from active transport (uses energy), predict the direction of diffusion and osmosis, and explain how controlling what crosses the selectively permeable membrane keeps internal conditions steady. Osmosis problems (hypotonic, hypertonic, isotonic) are a recurring item.
The selectively permeable membrane
Small, nonpolar molecules (oxygen, carbon dioxide) cross the bilayer easily. Charged ions and large polar molecules (like glucose) need transport proteins to cross.
Passive transport: no energy needed
Passive transport moves substances down their concentration gradient, from where they are more concentrated to where they are less concentrated, and needs no energy.
- Diffusion. The net movement of particles from high concentration to low concentration until evenly spread. Example: oxygen diffusing into a cell.
- Osmosis. The diffusion of water across a selectively permeable membrane, from where water is more concentrated (low solute) to where it is less concentrated (high solute).
- Facilitated diffusion. Passive movement of a substance down its gradient through a protein channel or carrier, used by molecules that cannot cross the bilayer alone. It still needs no energy.
Active transport: energy required
Active transport moves substances against their gradient, from low concentration to high, which diffusion cannot do. It requires energy (ATP) and uses membrane transport proteins (pumps). The classic example is the sodium-potassium pump in nerve cells. The exam clue for active transport is movement against the gradient or a statement that the cell uses energy.
Osmosis and tonicity
Osmosis problems are a staple EOC item. Compare the solute concentration inside the cell to the solution outside:
- Hypotonic solution (less solute outside than inside): water moves into the cell, so the cell swells (and an animal cell may burst).
- Hypertonic solution (more solute outside than inside): water moves out of the cell, so the cell shrinks.
- Isotonic solution (equal solute): no net water movement, so the cell stays the same size.
The single rule that solves these: water moves toward the higher solute concentration.
How transport maintains homeostasis
The link to homeostasis is the point of the standard. By controlling transport across the membrane, the cell keeps internal conditions (water balance, ion concentrations, nutrient levels, waste removal) within the narrow range its enzymes and processes need. For example, nerve cells use active transport (the sodium-potassium pump) to maintain the ion gradients that let them fire; root cells use active transport to take up minerals even when they are scarcer in the soil than in the cell. Passive transport handles routine gas exchange and water balance with no energy cost. Together, passive and active transport let the cell hold a steady internal state against a changing environment.
Try this
Q1. State the difference between diffusion and active transport in terms of energy and direction. [2 points]
- Cue. Diffusion needs no energy and moves substances down the gradient (high to low); active transport uses energy (ATP) and moves substances against the gradient (low to high).
Q2. A plant cell is placed in a hypertonic solution. State which way water moves and the effect on the cell. [2 points]
- Cue. Water moves out of the cell; the cell loses water and the vacuole shrinks (the cell becomes flaccid, and the membrane may pull away from the wall).
Exam-style practice questions
Practice questions written in the style of GaDOE exam questions on this dot point, with worked answer explainers. The year tag is the paper they imitate, not the source.
Milestones (style)1 marksA cell is placed in a solution with a higher solute concentration than the cell's interior (a hypertonic solution). What happens to the cell? (A) It swells as water enters. (B) It shrinks as water leaves. (C) Nothing, because the solution is isotonic. (D) It bursts.Show worked answer →
A 1-point selected-response item on osmosis.
The correct answer is B. In a hypertonic solution there is more solute (and therefore less water) outside the cell, so water moves out of the cell by osmosis, and the cell shrinks. A describes a hypotonic solution (water enters, the cell swells), C is wrong because the concentrations differ, and D (bursting) happens in a hypotonic solution, not a hypertonic one. The rule is that water moves toward the higher solute concentration.
Milestones (style)2 marksDrop-down. A molecule moves across the membrane from an area of low concentration to an area of high concentration. This movement is [transport type] and [requires / does not require] energy.Show worked answer →
A 2-point technology-enhanced (drop-down) item with two blanks.
The correct choices are "active transport" and "requires" energy. Movement from low to high concentration is against the concentration gradient, which only active transport can do, and moving against a gradient requires energy (ATP). If the molecule had moved from high to low concentration, the answer would be passive transport (diffusion), which does not require energy. The direction of movement relative to the gradient is the clue that decides the answer.
Related dot points
- Construct an explanation of how cell structures and organelles (nucleus, cytoplasm, cell membrane, cell wall, chloroplasts, lysosome, Golgi apparatus, endoplasmic reticulum, vacuoles, ribosomes, mitochondria) interact as a system to maintain homeostasis (GSE SB1.a).
A Georgia Milestones Biology EOC answer on the eukaryotic organelles as a structure-and-function system: the nucleus, ribosomes, endoplasmic reticulum, Golgi apparatus, mitochondria, chloroplasts, lysosomes, vacuoles, membrane, and cell wall, and how they work together to maintain homeostasis.
- Compare prokaryotic and eukaryotic cells, including the presence or absence of a membrane-bound nucleus and organelles, and explain the advantage of cellular compartmentalization (GSE SB1.a).
A Georgia Milestones Biology EOC answer comparing prokaryotic and eukaryotic cells: the membrane-bound nucleus and organelles, what the two cell types share, the advantage of compartmentalization, and the plant-animal-bacteria comparison the exam tests.
- Relate the structure of the four macromolecules (carbohydrates, lipids, proteins, nucleic acids), their monomers, and their functions in carrying out cellular processes (GSE SB1.c).
A Georgia Milestones Biology EOC answer on the four biological macromolecules: carbohydrates, lipids, proteins, and nucleic acids, their monomers and elements, their functions, and how structure relates to function in cellular processes.
- Illustrate the organization of interacting systems in multicellular organisms and explain how they maintain homeostasis through feedback, including the levels of organization from cells to organ systems (GSE SB4.a).
A Georgia Milestones Biology EOC answer on the organization of interacting body systems: the levels of organization (cells, tissues, organs, organ systems), how the major systems interact, and how negative feedback maintains homeostasis, with examples such as temperature and blood sugar regulation.
- Explain how enzymes (a type of protein) lower activation energy and carry out cellular processes, and how temperature, pH, and substrate fit affect enzyme activity (GSE SB1.c).
A Georgia Milestones Biology EOC answer on enzymes: how they lower activation energy, the lock-and-key specificity of the active site, the effect of temperature, pH, and substrate concentration, and what denaturation does to enzyme activity.
Sources & how we know this
- Biology Georgia Standards of Excellence (GSE) — Georgia Department of Education (2024)
- Georgia Milestones Biology EOC Assessment Guide — Georgia Department of Education (2024)