How do scientists read, copy, and change DNA, and why does it matter to society?
Describe applications of DNA technology, including gel electrophoresis, DNA fingerprinting, recombinant DNA, and genetically modified organisms, and evaluate their benefits and concerns (TEKS Biology, Reporting Category 2; cause and effect; structure and function).
A TEKS-level answer on biotechnology for the Texas STAAR Biology EOC: gel electrophoresis and DNA fingerprinting, recombinant DNA and genetic engineering, genetically modified organisms, and the benefits and concerns of these tools.
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What this topic is asking
The Biology TEKS ask you to describe applications of DNA technology and to evaluate their benefits and concerns. For STAAR Reporting Category 2 you need to recognize the main tools (gel electrophoresis, DNA fingerprinting, recombinant DNA, and genetically modified organisms), what each does, and how to weigh their advantages against their risks. This is a cause-and-effect and structure and function topic, and it often appears as a scenario asking you to identify a technology and judge its use.
Reading and comparing DNA
This banding pattern is the basis of DNA fingerprinting, comparing the DNA pattern of different samples. Because each person's DNA pattern is essentially unique (except identical twins), DNA fingerprinting is used in forensics (matching a sample to a suspect), in paternity testing, and in identifying remains. On STAAR, a gel diagram is often shown and you are asked which samples match.
Changing DNA: recombinant DNA and GMOs
Other examples include crops engineered to resist pests or to tolerate drought, and bacteria engineered to make medicines or break down pollutants. Genetic engineering differs from selective breeding: selective breeding works slowly over generations using existing variation, while genetic engineering directly inserts or alters a specific gene, often moving it between species.
Weighing benefits and concerns
The TEKS ask you to evaluate these technologies, which means giving both sides:
- Benefits. Reliable supplies of medicines (insulin, vaccines), higher crop yields, pest and disease resistance, identifying criminals and freeing the innocent, and diagnosing genetic disorders.
- Concerns. Possible effects of modified organisms on ecosystems and biodiversity, ethical questions about changing genes, concerns about who controls and can afford the technology, and questions about long-term safety.
A good evaluation names a specific benefit and a specific concern rather than saying simply that biotechnology is "good" or "bad."
Try this
Q1. State what gel electrophoresis separates DNA fragments by, and name one use. [2]
- Cue. By size (smaller fragments travel farther); used in DNA fingerprinting for forensics or paternity testing.
Q2. Describe one benefit and one concern of producing a genetically modified crop. [2]
- Cue. Benefit: higher yield or pest/disease resistance. Concern: possible effects on ecosystems or biodiversity, or ethical and access concerns.
Exam-style practice questions
Practice questions written in the style of TEA exam questions on this dot point, with worked answer explainers. The year tag is the paper they imitate, not the source.
STAAR Biology (2023 released style)1 marksGel electrophoresis separates fragments of DNA mainly according to which property? (A) Their color. (B) Their size (length). (C) The number of mutations they contain. (D) The species they came from.Show worked answer →
A 1-point multiple-choice item on gel electrophoresis.
The correct answer is B. Gel electrophoresis uses an electric field to move DNA fragments through a gel; smaller fragments travel farther, so fragments are separated by size. Color (A) is added later by stains, and C and D are not how the gel itself separates fragments.
Electrophoresis sorts DNA by size: small fragments move farthest.
STAAR Biology (2024 SCR style)2 marksA company inserts a human gene for insulin into bacteria so the bacteria produce human insulin for diabetics. Identify the technology used and explain one benefit of producing insulin this way. Support your answer.Show worked answer →
A 2-point short constructed response on recombinant DNA.
Full credit (2 points): this is recombinant DNA technology (genetic engineering), because a gene from one organism (human) is inserted into another (bacteria). A benefit is that the bacteria can be grown in large numbers to make a reliable, large supply of human insulin, which is safer and more consistent than older sources and helps people with diabetes.
Partial credit (1 point): names recombinant DNA without a clear benefit, or a benefit without naming the technology. The science is scored.
Related dot points
- Identify the components of DNA, describe the structure of the double helix and base pairing, and explain how DNA is replicated accurately before cell division (TEKS Biology, Reporting Category 2; structure and function; patterns).
A TEKS-level answer on DNA for the Texas STAAR Biology EOC: the components of a nucleotide, the double helix and complementary base pairing, and how DNA replication produces two identical copies before a cell divides.
- Describe how the information in DNA is used to build proteins through transcription and translation, and explain how the order of bases determines the order of amino acids (TEKS Biology, Reporting Category 2; cause and effect; structure and function).
A TEKS-level answer on protein synthesis for the Texas STAAR Biology EOC: transcription of DNA into mRNA, translation of codons into amino acids at the ribosome, and how the base sequence determines the protein and the trait.
- Apply Mendel's laws and use Punnett squares to predict the genotype and phenotype ratios of monohybrid crosses, and identify patterns of inheritance including dominant, recessive, codominant, and incomplete dominance (TEKS Biology, Reporting Category 2; patterns; using mathematics).
A TEKS-level answer on inheritance for the Texas STAAR Biology EOC: alleles, genotype and phenotype, dominant and recessive traits, using Punnett squares to predict ratios and probabilities, and codominance and incomplete dominance.
- Recognize the types of gene mutations and explain how a change in the DNA base sequence may be harmful, beneficial, or neutral and how it can be inherited (TEKS Biology, Reporting Category 2; cause and effect; stability and change).
A TEKS-level answer on mutations for the Texas STAAR Biology EOC: what a mutation is, substitution, insertion, and deletion, why an effect can be harmful, beneficial, or neutral, and how mutations in gametes are inherited and supply variation.
- Explain the role of meiosis in producing gametes with half the chromosome number and in generating genetic variation, and contrast meiosis with mitosis (TEKS Biology, Reporting Category 2; patterns; cause and effect).
A TEKS-level answer on meiosis for the Texas STAAR Biology EOC: chromosomes and the role of meiosis in halving the chromosome number, how crossing over and independent assortment create variation, and how meiosis differs from mitosis.
Sources & how we know this
- Texas Essential Knowledge and Skills for Science (Biology) — Texas Education Agency (2024)
- STAAR Biology Assessed Curriculum — Texas Education Agency (2024)