What does cell theory state, and how do prokaryotic and eukaryotic cells differ?
State the cell theory and the evidence for it, and distinguish prokaryotic from eukaryotic cells and plant from animal cells (Virginia 2018 Biology SOL BIO.3.a).
A SOL-level answer on cell theory for the Virginia Biology EOC: the three parts of cell theory and its evidence, the difference between prokaryotic and eukaryotic cells, and how plant and animal cells compare.
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What this topic is asking
Virginia Biology SOL standard BIO.3.a begins cell biology with the cell theory and the types of cells. The Biology EOC expects you to state the cell theory, know that it rests on evidence gathered with microscopes, and tell apart prokaryotic and eukaryotic cells, and plant and animal cells. This is foundational: nearly every later topic (organelles, transport, division) assumes you know what kind of cell you are dealing with.
The cell theory
The cell theory is a scientific theory, meaning it is a broad explanation supported by a large body of evidence. That evidence came from improvements in the microscope: Robert Hooke first described "cells" in cork, and later scientists observed living cells, leading to the conclusion that all organisms are cellular and that cells come only from other cells. This is a good example of how technology (the microscope) advances science and how a theory is built from many observations.
Prokaryotic and eukaryotic cells
The single biggest difference to remember is the nucleus: prokaryotes lack one, eukaryotes have one. Both cell types do share some features, a cell membrane, cytoplasm, ribosomes, and DNA, because all cells need to control what enters, hold their contents, make proteins, and store information. The EOC often gives a description or diagram and asks you to classify the cell.
Plant and animal cells
Both plant and animal cells are eukaryotic, so both have a nucleus and membrane-bound organelles. The differences are what plant cells have in addition:
- A cell wall outside the membrane, made of cellulose, giving the plant cell its rigid, boxy shape and support.
- Chloroplasts, the organelles of photosynthesis (animal cells cannot photosynthesize).
- A large central vacuole that stores water and helps keep the cell firm (turgid).
Animal cells lack all three. They tend to have a rounder shape and may have features such as centrioles. Knowing which structures are plant-only is a frequent EOC item, often as a drag-and-drop labeling task.
Try this
Q1. State the three parts of the cell theory. [3]
- Cue. All living things are made of cells; the cell is the basic unit of life; all cells come from pre-existing cells.
Q2. A cell has ribosomes, a cell membrane, and DNA, but no nucleus. Is it prokaryotic or eukaryotic, and how do you know? [2]
- Cue. Prokaryotic, because it lacks a nucleus (and membrane-bound organelles), even though it shares the membrane, ribosomes, and DNA common to all cells.
Exam-style practice questions
Practice questions written in the style of VDOE exam questions on this dot point, with worked answer explainers. The year tag is the paper they imitate, not the source.
VA Biology SOL (2023 released style)1 marksWhich statement is part of the cell theory? (A) All cells contain a nucleus. (B) All living things are made of one or more cells. (C) Cells can arise from nonliving matter. (D) Only animals are made of cells.Show worked answer →
A 1-point multiple-choice item on the cell theory.
The correct answer is B. The cell theory states that all living things are made of cells, the cell is the basic unit of life, and all cells come from existing cells. A is false (prokaryotes have no nucleus), C contradicts the theory (cells come from cells), and D ignores plants and other organisms.
The test rewards the three parts of the cell theory and rejects "cells arise from nonliving matter."
VA Biology SOL (2024 released style)2 marksA scientist examines two cells. Cell X has no nucleus and no membrane-bound organelles; cell Y has both. (a) Classify each cell as prokaryotic or eukaryotic. (b) State one further feature you would expect only in cell Y.Show worked answer →
A 2-point item on prokaryotic versus eukaryotic cells.
(a) 1 point: cell X is prokaryotic (no nucleus, no membrane-bound organelles); cell Y is eukaryotic.
(b) 1 point: any membrane-bound organelle expected only in the eukaryote, such as mitochondria, endoplasmic reticulum, Golgi apparatus, or (in a plant) chloroplasts; a true membrane-bound nucleus is also acceptable.
Markers reward the correct classification and one membrane-bound structure found in eukaryotes but not prokaryotes.
Related dot points
- Identify the major cell organelles and relate each structure to its function, showing how organelles work together to support life processes (Virginia 2018 Biology SOL BIO.3.a).
A SOL-level answer on organelles for the Virginia Biology EOC: the nucleus, mitochondria, ribosomes, endoplasmic reticulum, Golgi apparatus, chloroplasts, vacuoles, and cell wall, and how structure relates to function.
- Explain that the cell membrane is selectively permeable and describe passive transport (diffusion and osmosis) and active transport, including the role of concentration gradients (Virginia 2018 Biology SOL BIO.3.b).
A SOL-level answer on membrane transport for the Virginia Biology EOC: the selectively permeable phospholipid bilayer, diffusion and osmosis, active transport against the gradient, and predicting the direction water moves.
- Describe the cell cycle and mitosis as the process that produces two genetically identical cells for growth and repair, and relate uncontrolled cell division to cancer (Virginia 2018 Biology SOL BIO.3.c, BIO.3.d).
A SOL-level answer on the cell cycle for the Virginia Biology EOC: interphase and the stages of mitosis, why the two daughter cells are identical, the role of growth and repair, and how loss of control leads to cancer.
- Describe the structure of bacteria as prokaryotic cells, how they reproduce, and the beneficial and harmful roles they play in other organisms and the environment (Virginia 2018 Biology SOL BIO.4.b, BIO.4.d).
A SOL-level answer on bacteria for the Virginia Biology EOC: prokaryotic structure, rapid asexual reproduction, and the beneficial roles (decomposers, gut bacteria, nitrogen fixation) and harmful roles of bacteria.
- Develop and use models to explain and predict, judging their merits and limitations, and obtain, evaluate, and communicate scientific information from reliable sources (Virginia 2018 Biology SOL BIO.1.e, BIO.1.f).
A SOL-level answer on scientific models and communication for the Virginia Biology EOC: what models are and their limits, the difference between a hypothesis, theory, and law, and how to evaluate and communicate reliable scientific information.
Sources & how we know this
- 2018 Science Standards of Learning (Biology) — Virginia Department of Education (2018)
- SOL Practice Items (All Subjects) — Virginia Department of Education (2024)